Protein Purification
MilliporeSigma™ Calbiochem™ PARP Inhibitor XII
The PARP Inhibitor XII, also referenced under CAS 489457-67-2, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ β-Secretase Substrate IV, Fluorogenic
β-Secretase Substrate IV, Fluorogenic, is a highly sensitive FRET substrate. Hydrolysis of the substrate (Leu-Asp cleavage) by β-secretase results in fluorescence enhancement.
MilliporeSigma™ Calbiochem™ CBP-CREB Interaction Inhibitor
The CBP-CREB Interaction Inhibitor, also referenced under CAS 92-78-4, controls the biological activity of CBP-CREB.
MilliporeSigma™ Calbiochem™ Caspase-3/7 Inhibitor II
The Caspase-3/7 Inhibitor II, also referenced under CAS 775289-20-8, controls the biological activity of Caspase-3/7. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Urokinase Substrate III, Fluorogenic
Suitable for the quantitative direct fluorescent assay of urokinase.
MilliporeSigma™ Calbiochem™ Apicidin, Fusarium sp.
A potent, cell-permeable inhibitor of histone deacetylase (IC50 700 pM for parasitic histone deactetylase) that also exhibits antiprotozoal and potential anti-malarial properties.
MilliporeSigma™ Calbiochem™ NF-κB Activation Inhibitor
The NF-κB Activation Inhibitor, also referenced under CAS 545380-34-5, controls the biological activity of NF-κB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ SNX-482
A peptidyl toxin from venom of African tarantula, Hysterocrates gigas that acts as a high affinity, reversible blocker of Cav2.3 (α1E, R-type) channels (IC50 = 15-30 nM).
MilliporeSigma™ Calbiochem™ Ghrelin Receptor Antagonist, JMV 2959
A 1, 2, 4-triazole derived compound that acts as a potent ghrelin receptor (GHS-R1a) antagonist (IC50 = 32nM in a binding assay, dissociation constant Kb =
MilliporeSigma™ Calbiochem™ TCPOBOP
The most potent known member of the phenobarbital-like class of cytochrome P450 (CYP)-inducing agents.
MilliporeSigma™ Calbiochem™ Castanospermine, Castanospermum australe
Plant alkaloid inhibitor of several β-glucosidases and α-glucosidases, including those involved in N-linked processing of glycoproteins.
MilliporeSigma™ Calbiochem™ α-(Methylamino)isobutyric Acid
A glutamine transport inhibitor selective for Na+-dependent amino acid transport system A.
MilliporeSigma™ Calbiochem™ MRP1 Inhibitor II, Reversan
The MRP1 Inhibitor II, Reversan controls the biological activity of MRP1. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Cathepsin K Substrate II, Fluorogenic
An internally quenched, highly cathepsin K-selective, fluorogenic peptide substrate that is efficiently cleaved by CatK (
MilliporeSigma™ Calbiochem™ ERO1 Inhibitor II, EN460
A cell-permeable thiol reactive enone (EN) compound that selectively interacts with the active-site cysteine of reduced, active form of ERO1α and inhibits its activity (IC50